The study uses non-invasive brain stimulation (TMS-EEG) and (MRI) to investigate how stimulation at different brain waves can alter the brain's activity. The study involves 13 visits that include a clinical interview, screening questionnaires, MRI and 10 TMS-EEG sessions. During TMS-EEG, you will be comfortably seated wearing a fitted sensor cap that will be gelled. A coil will be positioned over difference areas of your brain and small pulses will be administered to record brain activity.
Eligibility Criteria
- You are between 18-65 years old
- You currently have depression
- You do not abuse alcohol or illegal substances
- You are fluent in the English language (spoken, written and reading)
- You have stated willingness to comply with all study procedures
- You do not have a history of a medical or neurological disorder that affects the central nervous system (such as traumatic brain injury, stroke, Parkinson)
- You do not have a history of seizures
- You can complete the MRI scan
- You do not have have serious or unstable medical condition requiring immediate investigation
What does the study involve?
- Number of contacts: 10+ sessions
- Format of Study: In-person
- Compensation offered: Yes
Investigator(s): Dr. Christoph Zrenner
Full Study Title: Real-Time EEG Triggered rTMS of the DLPFC: Identifying Brain State Targets in MDD
Contact Information:
E-mail: camhbrainstudy@camh.ca
REB number: 208/2023
REB Approval Expiry Date: June 12, 2027
PLEASE NOTE:
- Research staff cannot give medical advice over the phone or via email.
- If you have specific questions regarding your health care, please contact your family physician.
- We regret that not everyone screened for a study will be eligible to participate
- For more information about other treatment options for mental illness or addiction offered by CAMH, visit www.camh.ca or call 416-535-8501.